Immunohistochemical study of trophoblast cells using abortion material in the gestation period 9-12 weeks of pregnancy in women against the background of inflammatory diseases of the female genital organs

Abstract. This article is devoted to the results of studies trophoblast during gestation 9-12 weeks. study a fragment series immunohistochemical with TORCH infection, which are scheduled be carried out at different gestational dates. Purpose – in various types using method establish features expression metalloproteinase-2 abortion material period weeks pregnancy infection compared observations without an infectious process. Material and methods. The main group consisted 24 control - 22 aborted signs process (abortion for social reasons). examined gestation. microdensitometry specialized computer program ImageJ evaluated optical density color, procedure was performed on primary antibodies polymer antigen imaging system DAKO diaminobenzidine. Results. According age weeks, very observed invasive trophoblast, smallest syncytotrophoblast choric villi, both process, intermediate values noted chorionic villus cytotrophoblast cell column cytotrophoblast. Infection, reduced all four (cytotrophoblast villi; columns; endometrial fragments), except villi. Conclusions. largest syncytiotrophoblast indices villi columns. decreases excluding